The integrated structural biology platform of the center offers project-based access to all advanced tools from sample preparation and biophysical characterization to structural analysis including in particular cryo-EM, X-ray crystallography, small angle X-ray scattering, super-resolution fluorescence microscopy and NMR of proteins and macromolecular complexes including nucleoprotein complexes. Taken together, this allows integrating functional data and various multi-resolution structural data. These activities are supported by experienced engineers and technicians and by the strong scientific environment and know-how provided by the Department of Structural Biology of the center.
We are open to both academic and industrial partners in different ways, from simple services to research projects (collaborations).
Our centre (Instruct centre France 1) is part of infrastructures for Integrated Structural Biology:
-national infrastructure FRISBI https://frisbi.eu/
-european infrastructure Instruct-ERIC https://instruct-eric.org/ providing funded access to our platforms for Instruct users
-european infrastructure iNEXT-Discovery https://inext-discovery.eu/network/inext-d/services providing funded access to our Electron microscopy platform.
Our platform is labelised IBiSA (Infrastructure en Biologie Santé et Agronomie) and part of Research and Services Scientific core facilities Network Cortecs of the University of Strasbourg and of the Canceropole Grand Est.
In published material, you agree to acknowledge the use of the platform expertise using the following text:
This work used the Integrated Structural Biology platform of the Strasbourg Instruct-ERIC center IGBMC-CBI supported by FRISBI (ANR-10-INBS-0005-001).